Symptoms, Causes, Diagnosis, and Treatment

There are six types of systemic mastocytosis. Each type has different symptoms, but in general, the higher the abnormal mast cell accumulation, the greater the likelihood of serious health complications.

Indolent Systemic Mastocytosis (ISM)

Indolent (slower growing) systemic mastocytosis is the most common form of systemic mastocytosis in adults. People usually have milder symptoms that develop over many years. Skin and gastrointestinal issues are common, and usually other organs aren’t affected.